IgA nephropathy classification
Classification
Primary IgA Nephropathy
When IgA nephropathy occurs alone, it is called "primary IgA nephropathy". It is thus not secondary to any chronic concomitant disease. Before the diagnosis of primary IgA nephropathy is made, secondary causes need to be ruled out.
Secondary IgA Nephropathy
Normal 0 false false false EN-US JA X-NONE Normal 0 false false false EN-US JA X-NONE When IgA nephropathy occurs secondary to other chronic or systemic diseases, it is called “secondary IgA nephropathy”. Secondary causes of IgA nephropathy should be ruled out because secondary causes may alter management plans and probably prognosis too. Common primary etiologies associated with glomerular IgA deposits and thus secondary IgA nephropathy include the following:
The most important 3 causes are:
- Liver cirrhosis[1]
- Celiac disease[1]
- HIV infection[1]
IgA nephropathy has also been associated with the following diseases, but to a much less extent:
- Dermatitis herpetiformis[1]
- Seronegative arthritis, especially as ankylosing spondylitis[1]
- Small-cell carcinoma[1]
- Hodgkin’s lymphoma[1]
- T-cell lymphoma, such as mycosis fungoides[1]
- Disseminated tuberculosis[1]
- Bronchiolitis obliterans[1]
- Inflammatory bowel disease (Crohn’s disease and ulcerative colitis)[1]
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