IgA nephropathy causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Causes

IgA is a protein that helps the body fight infections. IgA nephropathy (Berger's disease) occurs when too much of this protein is deposited in the kidneys. IgA builds up inside the small blood vessels of the kidney. Structures in the kidney called glomeruli become inflamed.

IgA nephropathy (Berger's disease) is a form of mesangial proliferative nephritis.

The disorder can appear suddenly (acute), or progress slowly over many years (chronic glomerulonephritis).