Calciphylaxis medical therapy

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Calciphylaxis Microchapters

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Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Calciphylaxis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Biopsy

Treatment

Medical Therapy

Surgery

Prevention

Cost-Effectiveness of Therapy

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The optimal treatment is prevention. Rigorous and continuous control of phosphate and calcium balance most probably will avoid the metabolic changes which may lead to calciphylaxis. There is no specific treatment. Of the treatments that exist, none is internationally recognised as the standard of care.

Medical Therapy

An acceptable treatment could include:

  • Dialysis (the number of sessions may be increased)
  • Intensive wound care
  • Adequate pain control
  • Correction of the underlying plasma calcium and phosphorus abnormalities (lowering the Ca x P product below 55 mg2/dL2)
  • Avoiding (further) local tissue trauma (including avoiding all subcutaneous injections, and all not-absolutely-necessary infusions and transfusions)

References


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