Hypermagnesemia causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Causes
- Since magnesium is excreted through the kidneys, renal failure can result in hypermagnesemia. The most important cause however is suppletion.
- Hemolysis, magnesium concentration in erythrocytes is approximately three times greater than in serum, therefore hemolysis can increase plasma magnesium. Hypermagnesemia is expected only in massive hemolysis.
- Renal insufficiency, excretion of magnesium becomes impaired when creatinine clearance falls below 30 ml/min. However, hypermagnesemia is not a prominent feature of renal insufficiency unless magnesium intake is increased.
- Other conditions that can predispose to mild hypermagnesemia are diabetic ketoacidosis, adrenal insufficiency, hyperparathyroidism and lithium intoxication.