Cardiac disease in pregnancy contraindications to pregnancy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Absolute and relative contraindications to pregnancy include severe pulmonary arterial hypertension; severe fixed valve stenoses (AS,MS,PS,HOCM, coarctation; Class III or IV congestive heart failure with a left ventricular ejection fraction of < 40%; a history of peripartum cardiomyopathy; a dilated aorta such as in Marfan's syndrome with an aortic arch >40-45 mm; and severe cynaosis.
Conditions in Which Pregnancy is Advised Against
- Severe pulmonary arterial hypertension
- Severe fixed obstructive lesions such as aortic stenosis, mitral stenosis, pulmonic stenosis, hypertrophic obstructive cardiomyopathy, coarctation of the aorta
- Left ventricular systolic dysfunction
- Class III or IV CHF, EF <40%
- Prior peripartum cardiomyopathy
- Dilated or unstable aorta
- Marfan's syndrome with aorta ≥40-45 mm
- Severe cyanosis