Brugada syndrome classification

Brugada syndrome Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Differentiating Brugada syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Examples of Type I Brugada Syndrome
Chest X Ray
Echocardiography or Ultrasound
Electrophysiologic Studies
Genetic Testing
Treatment
Treatment
Drugs to Avoid
Drugs to Preferably Avoid
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Brugada syndrome classification On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Brugada syndrome classification All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Brugada syndrome classification
CDC on Brugada syndrome classification
Brugada syndrome classification in the news
Blogs on Brugada syndrome classification
Directions to Hospitals Treating Brugada syndrome
Risk calculators and risk factors for Brugada syndrome classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

There are three electrocardiographic patterns in Brugada syndrome (Type1,2,3).

Classification

1. Type 1 ST segment elevation is diagnostic of Brugada syndrome and is characterized by a coved ST-segment elevation ≥2 mm (0.2 mV) followed by a negative T wave.
2. Type 2 ST-segment elevation has a saddleback appearance with a high take-off ST-segment elevation of ≥2 mm followed by a trough displaying ≥1 mm ST elevation followed by either a positive or biphasic T wave.
3. Type 3 ST-segment elevation has either a saddleback or coved appearance with an ST-segment elevation of <1 mm.

File:Brugada 3.1.jpg

ECG pattern in Brugada syndrome. According to a recent consensus document, type 1 ST segment elevation either spontaneously present or induced with Ajmaline/Flecainide test is considered diagnostic. Type 1 and 2 may lead to suspicion but drug challenge is required for diagnosis. The ECGs in the right and left panels are from the same patient before (right panel, type 1) and after (left panel, type 1) endovenous administration of 1 mg/kg of Ajmaline during 10 minutes.