Trifascicular block

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

The His-Purkinje system is a trifascicular system, with bifascicular block referring to conduction delay within either both the right bundle and left anterior or posterior fascicle or the left bundle branch in itself. Trifascicular block refers to first degree AV block, Right Bundle Branch Block, and Left Anterior Hemiblock

Trifascicular block is a problem with the electrical conduction of the heart. It is diagnosed on an electrocardiogram (ECG/EKG) and has three features: [1]

Alternatively, trifascicular block is suggested by alternating right bundle branch block and left bundle branch block.

Differentiating Trifascicular block from other Disorders

Trifascicular block is important to diagnose because it is difficult to tell based on the surface ECG whether the prolonged PR interval is due to disease in the AV node or due to diffuse distal conduction system disease.

  • In the former case, if the block at the AV node level becomes complete, the escape rhythm will originate from the bundle of His, which typically will generate heart rates in the 40s, allowing the individual to survive and complain of symptoms of fatigue or near-syncope to their physician.
  • In the later case, however, because the conduction system disease is diffuse in nature, the escape rhythm may be fascicular or ventricular, which may be at rates that are life-threateningly low.

Diagnosis

The diagnosis of whether the PR prolongation is due to AV nodal disease or diffuse conduction system disease is typically made by an electrophysiologic study of the conduction system. In an electrophysiologic study, trifascicular block due to AV nodal disease is represented by a prolonged AH interval (denoting prolonged time from impulse generation in the atria and conduction to the bundle of His) with a relatively preserved HV interval (denoting normal conduction from the bundle of His to the ventricles). Trifascicular block due to distal conduction system disease is represented by a normal AH interval and a prolonged HV interval.

EKG


The EKG below is recorded in an elderly man with a history of syncope.

This electrocardiogram shows sinus rhythm at 74 per minute. The PR interval is grossly prolonged at 288 milliseconds, there's an RSR complex in V1 compatible with a right bundle branch block and a QRS axis of minus 83 degrees compatible with a left anterior hemi-block. Taking all three abnormalities together the tracing suggests a trifasicular block.

This patient also had a Holter monitor that showed second-degree heart block and as a result a pacemaker was implanted because of his history of syncope.


The EKG below is a regular rhythm with a ventricular rate of 70/min. The QRS has a left axis deviation and a dominant R wave in V1. The PR interval is 260 ms. This tracing suggests a first degree heart block with a left anterior hemi block and RBBB. This has been called Trifasicular block.

Treatment

The treatment for diffuse distal conduction system disease is insertion of a pacemaker. If the PR prolongation is due to AV nodal disease, a case may be made for observation, as it may never progress to complete heart block with life threateningly low heart rates.

Regardless of where in the conduction system the block is, if the block is believed to be the cause of syncope in an individual, a pacemaker is an appropriate treatment.

Sources

Copyleft images obtained courtesy of ECGpedia, http://en.ecgpedia.org/index.php?title=Special:NewFiles&dir=prev&offset=20080806182927&limit=500

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