Diastolic dysfunction causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-in-Chief: Rim Halaby

Overview

Diastolic dysfunction is the mechanical abnormality of the heart to properly relax and fill with blood during diastole. Several medical conditions may lead to diastolic dysfunction and they include impaired myocardial relaxation, increased myocardial stiffness and extrinsic constraint on the heart.

Causes

• Aortic stenosis
• Diabetes
• Hypertrophic heart diseases(for example, as seen in hypertension)
• Hypertrophic obstructive cardiomyopathy (HOCM)
• Infiltrative diseases ( for example, amyloidosis)
• Ischemia
• Mitral stenosis
• Pericardial compression
• Restrictive cardiomyopathy
• Systolic dysfunction