Septic arthritis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Jumana Nagarwala, M.D., Senior Staff Physician, Department of Emergency Medicine, Henry Ford Hospital; Cafer Zorkun, M.D., Ph.D. [2]

Overview

Laboratory Findings

The diagnosis of septic arthritic can be difficult as no test is able to completely rule out the possibility.

A number of factors should increase ones suspicion of the presence of an infection. In children these are: fever > 38.5 C, non weight bearing, serum WCBs > 12 x 10^9, ESR > 40 mm/hr, CRP > 20 mg/dL, a previous visit for the same.

Joint Fluid Aspiration

Diagnosis is by aspiration (giving a turbid, non-viscous fluid), Gram stain and culture of fluid from the joint, as well as tell-tale signs in laboratory testing (such as a highly elevated neutrophils (approx. 90%), ESR or CRP). A proportion of patients with septic arthritis have little in the way of fever or raised ESR, although the CRP is usually raised [1]

Gram Stain

The Gram stain can rule in the diagnosis of septic arthritis however cannot exclude it.[2]

References

  1. Geirsson AJ, Statkevicius S, Víkingsson A (2008). "Septic arthritis in Iceland 1990-2002: increasing incidence due to iatrogenic infections". Ann Rheum Dis. 67 (5): 638–43. doi:10.1136/ard.2007.077131. PMID 17901088. Unknown parameter |month= ignored (help)
  2. "BestBets: Is a negative gram stain in suspected septic arthritis sufficient to rule out septic arthritis".


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