Mycoplasma pneumonia historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In humans, Mycoplasma pneumoniae was first described by Hobart A. Reimann in 1938 in a patient with a self-limited “atypical” pneumonia.

Historical Perspective

  • In 1898, Mycoplasma was first isolated in cattle.
  • In humans, Mycoplasma pneumoniae was first described by Hobart A. Reimann in 1938 in a patient with a self-limited “atypical” pneumonia.[1]
  • In 1943, Reimann first described the phenomenon of cold agglutination.
  • It was first thought to be a virus or fungus, which is why the organism is referred to as Mycoplasma (Greek for “fungus-formed”).
  • In 1944, Eaton reported Eaton's agent as the primary cause of atypical pneumonia.[2] In 1961, M. pneumoniae was discovered to be Eaton's agent.

References

  1. Reimann HA (1984). "Landmark article Dec 24,1938: An acute infection of the respiratory tract with atypical pneumonia. A disease entity probably caused by a filtrable virus. By Hobart A. Reimann". JAMA. 251 (7): 936–44. PMID 6363732.
  2. Eaton MD, Meiklejohn G, van Herick W (1944). "STUDIES ON THE ETIOLOGY OF PRIMARY ATYPICAL PNEUMONIA : A FILTERABLE AGENT TRANSMISSIBLE TO COTTON RATS, HAMSTERS, AND CHICK EMBRYOS". J Exp Med. 79 (6): 649–68. PMC 2135382. PMID 19871393.

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