Retinitis pathophysiology

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=Cytomegalovirus

• Retinitis, caused by cytomegalovirus (CMV), involves the infection of all layers of the retinal tissue.
• Spread of the the infection will occur at approximately 24 nanometers per day.
• Primarily infected areas include the RPE and the subjacent choroid.
• Infection will consist of a vast amount of cellular necrosis across the retina; with the enlargement of infected cells, evidently hosting viral inclusions.
• CMV retinitis, post-treatment, will commonly persist on the previously scarred, retinal tissue.