Donovanosis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]; Nate Michalak, B.A.

Laboratory Findings

It may be donovanosis if genital sores have been present for a long time and have been spreading.
Tests that may be done include:
- Culture of tissue sample: Culture of C. granulomatis is difficult to perform and not routinely available.
- Scrapings or punch biopsy of lesion: Diagnosis requires visualization of Donovan bodies (numerous bacilli in the cytoplasm of macrophage demonstrated with Giemsa or Wright’s stain) in smears of scrapings from the ulcer base or histologic sections.
Laboratory tests, such as those used to detect syphilis, are available only on a research basis for diagnosing donovanosis.