Otitis externa other imaging findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Other imaging findings
Nuclear Scintigraphy
- For malignant otitis externa, Technetium-99m-based scintigraphy will reveal the extent of the infectious damage on the temporal and intracranial bones.[1]
- Tc-99m analysis will display findings of activity of osteoblast cells that are indicative of infection from malignant otitis externa.[2]
- Additionally, Gallium Citrate Ga 67 scans will reveal extent of the spread of malignant otitis externa infection.
- The gallium citrate is absorbed by the macrophages and reticular endothelial cells in the areas of the temporal or intracranial bones that display markers for inflammation.
- Gallium Citrate Ga 67 is preferred to Technetium-99m for scintigraphic scans due to the tendency of Tc-99m to be overly sensitive to osteoblast activity, often resulting in positive malignant otitis externa results prematurely, as well as displaying lingering positive results after the infection is treated.
References
- ↑ Leahy TW, Sader C (2011). "A rare case of bilateral malignant otitis externa and osteomyelitis with lower cranial nerve sequelae". BMJ Case Rep. 2011. doi:10.1136/bcr.03.2011.3957. PMC 3094778. PMID 22696730.
- ↑ Chen JC, Yeh CF, Shiao AS, Tu TY (2014). "Temporal bone osteomyelitis: the relationship with malignant otitis externa, the diagnostic dilemma, and changing trends". ScientificWorldJournal. 2014: 591714. doi:10.1155/2014/591714. PMC 4052568. PMID 24963511.