Nephritic syndrome epidemiology and demographics
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Acute glomerulonephritis accounts for 10-15% of glomerular diseases in the USA.(0) The reported incidence rates of glomerulonephritis in adults varies between 0.2 to 2.5/100,000 annually. Approximately 25% of patients with acute glomerulonephritis present with nephritic syndrome. The most common cause of glomerulonephritis worldwide is IgA nephropathy (Berger disease). Approximately 25-30% of patients eventually develop end-stage renal disease (ESRD).
The yearly variation of incidence of glomerulonephritis is not validated. While some studies report a decrease in the incidence due to improved healthcare and socioeconomic status, others report an increase in the reported incidence due to increased number of biopsies.(0) Additionally, the true incidence is difficult to predict because the disease might present subclinically in more than 50% of the patients.