Dilated cardiomyopathy laboratory findings
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Most of the laboratory workup for dilated cardiomyopathy is usually targeted towards detecting the cause.[1]
- Thyroid function tests
- Comprehensive metabolic panel
- Workup for anemia (CBC and iron studies)
- Urine toxicology screening
- Some drugs as cocaine and amphetamine increase the risk of dilated cardiomyopathy
- Genetic screening
- Usually reserved as the last step.
- May identify genetic/inherited causes of dilated cardiomyopathy.
Other laboratory investigations may target the severity of the condition or its effect on the cardiac function.
- Cardiac biomarkers (troponin and CK-MB)
- Brain natriuretic peptide (BNP)
Other biomarkers currently under investigation include:
- Uric acid (persistently elevated)
- Osteopontin
- Ca-125
- Pro-inflammatory cytokines (as tumor necrosis factor-α and interleukin-6)[2]
References
- ↑ Japp AG, Gulati A, Cook SA, Cowie MR, Prasad SK (2016). "The Diagnosis and Evaluation of Dilated Cardiomyopathy". J Am Coll Cardiol. 67 (25): 2996–3010. doi:10.1016/j.jacc.2016.03.590. PMID 27339497.
- ↑ Bielecka-Dabrowa A, Wierzbicka M, Dabrowa M, Goch A (2008). "New methods in laboratory diagnostics of dilated cardiomyopathy". Cardiol J. 15 (4): 388–95. PMID 18698552.