Pemberton's sign

Pemberton's sign

WikiDoc Resources for Pemberton's sign
Articles
Most recent articles on Pemberton's sign Most cited articles on Pemberton's sign Review articles on Pemberton's sign Articles on Pemberton's sign in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Pemberton's sign Images of Pemberton's sign Photos of Pemberton's sign Podcasts & MP3s on Pemberton's sign Videos on Pemberton's sign
Evidence Based Medicine
Cochrane Collaboration on Pemberton's sign Bandolier on Pemberton's sign TRIP on Pemberton's sign
Clinical Trials
Ongoing Trials on Pemberton's sign at Clinical Trials.gov Trial results on Pemberton's sign Clinical Trials on Pemberton's sign at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Pemberton's sign NICE Guidance on Pemberton's sign NHS PRODIGY Guidance FDA on Pemberton's sign CDC on Pemberton's sign
Books
Books on Pemberton's sign
News
Pemberton's sign in the news Be alerted to news on Pemberton's sign News trends on Pemberton's sign
Commentary
Blogs on Pemberton's sign
Definitions
Definitions of Pemberton's sign
Patient Resources / Community
Patient resources on Pemberton's sign Discussion groups on Pemberton's sign Patient Handouts on Pemberton's sign Directions to Hospitals Treating Pemberton's sign Risk calculators and risk factors for Pemberton's sign
Healthcare Provider Resources
Symptoms of Pemberton's sign Causes & Risk Factors for Pemberton's sign Diagnostic studies for Pemberton's sign Treatment of Pemberton's sign
Continuing Medical Education (CME)
CME Programs on Pemberton's sign
International
Pemberton's sign en Espanol Pemberton's sign en Francais
Business
Pemberton's sign in the Marketplace Patents on Pemberton's sign
Experimental / Informatics
List of terms related to Pemberton's sign

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pemberton's sign is the development of facial plethora, distended neck and head superficial veins, inspiratory stridor and elevation of the jugular venous pressure (JVP) upon raising of the patient's both arms above his/her head simultaneously, as high as possible (Pemberton's maneuver).

Causes

A positive Pemberton's sign is a sign of superior vena cava syndrome, possibly from a mass in the mediastinum, usually caused by a tumor or goiter.

Apical lung cancers often cause a positive Pemberton's sign and a high index of suspicion should be maintained in patients with symptoms of dyspnea and facial plethora with an extensive smoking history.

References

• Pemberton HS. Sign of submerged goitre. Lancet 1946;251:509.