Hypophosphatemia history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

History and Symptoms

• Muscle weakness. This occurs in major muscles, but also may manifest as diplopia, low cardiac output (including myonecrosis and cardiomyopathy, dysphagia, and respiratory depression due to respiratory muscle weakness).
• Mental status changes. This may range from irritability to gross confusion, delirium, and coma.
• White cell dysfunction, causing worsening of infections
• Instability of cell membrates due to low ATP levels: this may cause rhabdomyolysis with increased CPK, and also hemolytic anemia.