Interstitial nephritis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Mohsen Basiri M.D.
Overview
The majority of patients with AIN from any cause are asymptomatic., or patients may present with nonspecific signs and
symptoms of acute renal dysfunction. These may include the acute or subacute
onset of nausea, vomiting, and malaise
Patients may be oliguric; in a retrospective study that included 60 cases of AIN (92 percent of which were drug induced, with the
remainder idiopathic), oliguria was present among 51 percent [11]. Gross hematuria occurs in approximately 5 percent of individuals [
OR
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
At times there are no symptoms of this disease, but when they do occur they are widely varied and can occur rapidly or gradually.[1][2][3][4][5] When caused by an allergic reaction, the symptoms of acute tubulointerstitial nephritis are fever (27% of patients),[2] rash (15% of patients),[2] and enlarged kidneys. Some people experience dysuria, and lower back pain. In chronic tubulointerstitial nephritis the patient can experience symptoms such as nausea, vomiting, fatigue, and weight loss. Other conditions that may develop include hyperkalemia, metabolic acidosis, and kidney failure.
References
- ↑ Rossert J (2001). "Drug-induced acute interstitial nephritis". Kidney Int. 60 (2): 804–17. doi:10.1046/j.1523-1755.2001.060002804.x. PMID 11473672.
- ↑ 2.0 2.1 2.2 .
- ↑ Pusey C, Saltissi D, Bloodworth L, Rainford D, Christie J (1983). "Drug associated acute interstitial nephritis: clinical and pathological features and the response to high dose steroid therapy". Q J Med. 52 (206): 194–211. PMID 6604293.
- ↑ Handa S (1986). "Drug-induced acute interstitial nephritis: report of 10 cases". CMAJ. 135 (11): 1278–81. PMID 3779558.
- ↑ Buysen J, Houthoff H, Krediet R, Arisz L (1990). "Acute interstitial nephritis: a clinical and morphological study in 27 patients". Nephrol Dial Transplant. 5 (2): 94–9. PMID 2113219.