Idiopathic thrombocytopenic purpura history and symptoms

Jump to navigation Jump to search

Idiopathic thrombocytopenic purpura Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Idiopathic thrombocytopenic purpura from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Radiation

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Idiopathic thrombocytopenic purpura history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Idiopathic thrombocytopenic purpura history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Idiopathic thrombocytopenic purpura history and symptoms

CDC on Idiopathic thrombocytopenic purpura history and symptoms

Idiopathic thrombocytopenic purpura history and symptoms in the news

Blogs on Idiopathic thrombocytopenic purpura history and symptoms

Directions to Hospitals Treating Idiopathic thrombocytopenic purpura

Risk calculators and risk factors for Idiopathic thrombocytopenic purpura history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

History and Symptoms

ITP is usually chronic in adults[1] and the probability of durable remission is 20–40%.[2] Usually, ITP patients suffer from bruising, petechiae, nosebleeds and bleeding gums may occur if the platelet count is below 20,000,[3] compared to a normal range of 150,000–400,000 per mm3.

Evan's syndrome can occur in ~1% of cases and manifests by an autoimmune (Coombs +) hemolytic anemia with ITP.

Symptoms include:

  • Abnormally heavy menstruation
  • Bleeding into the skin causing a characteristic skin rash that looks like pinpoint red spots (petechial rash)
  • Easy bruising
  • Nosebleed or bleeding in the mouth

References

  1. Cines DB, Blanchette VS (2002). "Immune thrombocytopenic purpura". N. Engl. J. Med. 346 (13): 995–1008. doi:10.1056/NEJMra010501. PMID 11919310.
  2. Stevens W, Koene H, Zwaginga JJ, Vreugdenhil G (2006). "Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights". The Netherlands journal of medicine. 64 (10): 356–63. PMID 17122451.
  3. Cines DB, McMillan R (2005). "Management of adult idiopathic thrombocytopenic purpura". Annu. Rev. Med. 56: 425–42. doi:10.1146/annurev.med.56.082103.104644. PMID 15660520.

Template:WH Template:WS