Tetralogy of fallot epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2], Keri Shafer, M.D. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

Tetralogy of Fallot represents 5-7% of congenital heart defects. Tetralogy of Fallot is the most common cause of cyanotic heart disease and accounts for one third of all cases of cyanotic heart disease.

Epidemiology and Demographics

Prevalance

• Tetralogy of Fallot occurs in approximately 30 to 60 per 100,000 births.
• It represents 5-7% of congenital heart defects.

Incidence

• The majority of cases are thought to be sporadic and are not familial.
• The incidence in siblings is 1% to 5%.

Gender

• Tetralogy of Fallot occurs slightly more often in males than in females.

References

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