Pyelonephritis overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pyelonephritis is an ascending urinary tract infection that has reached the pyelum (pelvis) of the kidney (nephros in Greek). If the infection is severe, the term "urosepsis" is used interchangeably (sepsis being a systemic inflammatory response syndrome due to infection). It requires antibiotics as therapy, and treatment of any underlying causes to prevent recurrence. It is a form of nephritis. It can also be called pyelitis..

Epidemiology and Demographics

Pyelonephritis is very common, with 120-130 cases annually per 100,000 women and 30-40 cases per 100,000 men.