Menopause pathophysiology

Menopause happens normally as women age, And the main cause of the menopause is the natural depletion of the primary follicles (oocytes) in the ovaries and And the decline of the response of ovaries to anterior pituitary gonads hormones that include follicles stimulating hormones(FSH) and luteinizing hormones(LH). These hormones stimulate the ovaries to produce of estrogen and progesterone hormones in a cyclic pattern under the control of hypothalamus that secrets of the gonadotropin-releasing hormones which stimulate anterior pituitary gonads hormone secretion in addition to feedback mechanism by inhibin

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