Iron deficiency anemia other diagnostic studies
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Overview
Other Diagnostic Studies
Bone Marrow Aspiration
Conventionally, a definitive diagnosis requires a demonstration of depleted body iron stores obtained by bone marrow aspiration, with the marrow stained for iron.[1][2] Because this is invasive and painful, while a clinical trial of iron supplementation is inexpensive and not traumatic, patients are often treated based on clinical history and serum ferritin levels without a bone marrow biopsy. Furthermore, a study published April 2009[3] questions the value of stainable bone marrow iron following parenteral iron therapy.
Colonoscopy
May be done to look for the cause of iron deficiency:
- Celiac disease
- Crohn's disease
Upper Endoscopy
May be done to look for the site of bleeding.
References
- ↑ Mazza, J. (21 October 1978). "Usefulness of the serum ferritin concentration in the detection of iron deficiency in a general hospital". Canadian Medical Association Journal. 119 (8): 884–886. PMC 1819106. PMID 737638. Retrieved 2009-05-04. Unknown parameter
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ignored (help) - ↑ Kis, AM (1998). "Detecting Iron Deficiency in Anemic Patients with Concomitant Medical Problems". J Gen Intern Med. 13 (7): 455–61. doi:10.1046/j.1525-1497.1998.00134.x. PMC 1496985. PMID 9686711. Unknown parameter
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ignored (help) - ↑ Thomason, Ronald W. (2009). "Evidence That Stainable Bone Marrow Iron Following Parenteral Iron Therapy Does Not Correlate With Serum Iron Studies and May Not Represent Readily Available Storage Iron". American Journal of Clinical Pathology. 131 (4): 580–585. doi:10.1309/AJCPBAY9KRZF8NUC. PMID 19289594. Retrieved 2009-05-04. Unknown parameter
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