Restless legs syndrome
Restless legs syndrome | |
Sleep pattern of a Restless Legs Syndrome patient (red) vs. a healthy sleep pattern (blue). |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Synonyms and keywords: Wittmaack-Ekbom's syndrome; RLS
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Restless legs syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Other Diagnostic Studies
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Controversies
Recently, several major pharmaceutical companies are reported to be marketing drugs without an explicit approval for RLS, which are "off-label" applications for drugs approved for other diseases. The Restless Leg Foundation [1] received 44% of its $1.4 million in funding from these pharmaceutical groups[2]. This has called into question the neutrality of this group (significant conflict of interest issue) and the course of action which they recommend to RLS patients.
Related Chapters
References
Template:Diseases of the nervous system
ca:Síndrome de les cames neguitoses de:Restless-Legs-Syndrom ms:Sindrom kaki resah fi:Levottomat jalat sv:Rastlösa ben