Elastase in blood serum
| Elastase in blood serum |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
- The presence of elastase in the blood serum is caused by serine proteinase hydrolyzing elastic occuring in the endothelial cells, macrophages, and granulocytes
| Reference Range | |
| In Plasma | 60-110 ng/ml |
| In Pleural Effusion | 480-2900 ng/ml |
Causes of decreased elastase in blood serum
Causes of increased elastase in blood serum[3][4]
Common Causes
- Acute lung injury[5]
- Ischemia-Reperfusion Injury[6]
- Neutrophilic asthma[7]
- Chronic joint disorders
- Hemodialysis
- Multiple trauma
- Sepsis
- Shock
- Shock lung in pre-eclampsia
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
References
- ↑ Stegenga, ME.; van der Crabben, SN.; Blümer, RM.; Levi, M.; Meijers, JC.; Serlie, MJ.; Tanck, MW.; Sauerwein, HP.; van der Poll, T. (2008). "Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia". Blood. 112 (1): 82–9. doi:10.1182/blood-2007-11-121723. PMID 18316629. Unknown parameter
|month=ignored (help) - ↑ de Kruif, MD.; Lemaire, LC.; Giebelen, IA.; van Zoelen, MA.; Pater, JM.; van den Pangaart, PS.; Groot, AP.; de Vos, AF.; Elliott, PJ. (2007). "Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia". J Immunol. 178 (3): 1845–51. PMID 17237435. Unknown parameter
|month=ignored (help) - ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ Donnelly, SC.; MacGregor, I.; Zamani, A.; Gordon, MW.; Robertson, CE.; Steedman, DJ.; Little, K.; Haslett, C. (1995). "Plasma elastase levels and the development of the adult respiratory distress syndrome". Am J Respir Crit Care Med. 151 (5): 1428–33. doi:10.1164/ajrccm.151.5.7735596. PMID 7735596. Unknown parameter
|month=ignored (help) - ↑ Hughes, SF.; Cotter, MJ.; Evans, SA.; Jones, KP.; Adams, RA. (2006). "Role of leucocytes in damage to the vascular endothelium during ischaemia-reperfusion injury". Br J Biomed Sci. 63 (4): 166–70. PMID 17201205.
- ↑ Baines, KJ.; Simpson, JL.; Wood, LG.; Scott, RJ.; Gibson, PG. (2011). "Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma". Thorax. 66 (11): 942–7. doi:10.1136/thx.2010.157719. PMID 21785157. Unknown parameter
|month=ignored (help)