Neonatal lupus erythrematosus

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Overview

congenital heart block (CCHB) accompanied with neonatal lupus erythematosus is caused by an immune reaction between maternal anti-Ro/SSA antibodies and the fetal heart and is generally considered an irreversible process. This reaction mostly occurs before 30 weeks' gestation, especially between the 20th and 24th week.[1]

  1. Isayama T, Inamura N, Shiono N, Kitajima H (2013). "Neonatal lupus erythematosus complicated by improved congenital complete heart block". Pediatr Int. 55 (4): 521–4. doi:10.1111/ped.12073. PMID 23910804.