High D-dimer causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Elevated levels of D-dimer signify the activation of hemostasis and fibrinolytic pathway. It is a non-specific marker that has been widely implicated in acute venous thromboembolism (VTE). However, D-dimer levels are also increased in patients with other conditions, such as cancer, pregnancy, infections, trauma, and recent surgery.[1]
Causes
- Age
- Aortic dissection
- Atherosclerosis
- Atrial fibrillation
- Heart failure
- Ischemic heart disease
- Liver disease
- Malignancy
- Pregnancy
- Primary pulmonary hypertension
- Renal disease
- Sickle cell disease
- Stroke
- Surgery
- Thromboembolism
- Trauma
References
- ↑ Lippi G, Franchini M, Targher G, Favaloro EJ (2008). "Help me, Doctor! My D-dimer is raised". Ann Med. 40 (8): 594–605. doi:10.1080/07853890802161015. PMID 18608117.