Nephrotic syndrome causes

Nephrotic Syndrome Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Primary Causes

Primary renal disorders, such as primary glomerulonephritides, may cause primary nephrotic syndrome. Differentiation between different types of glomerular diseases is often made by clinical suspicion and by renal biopsy, which includes light microscopy, immunofluorescence, and ideally electron microscopy.

Secondary Causes

Secondary causes of renal disorders cause secondary nephrotic syndrome. These conditions must always be considered in the differential diagnosis of nephrotic syndrome.

Secondary Causes by Histologic Pattern

List of Secondary Causes of Nephrotic Syndrome

Glomerulonephritis with Nephrotic Syndrome

• Captopril
• Cancer
• Diabetes Mellitus
• Drugs
• Hepatitis B
• Hodgkin's Lymphoma
• Mixed Connective Tissue Disease
• Penicillamine
• Streptococcal throat infection
• Systemic Lupus Erythematosus
• Thyroiditis

Acute Glomerulonenephritis

• Berger's Disease
• Goodpasture's Syndrome
• Henoch-Schonlein Syndrome
• Streptococcal Infections
• Shunt Infections
• Subacute Endocarditis
• Systemic Lupus Erythematosus
• Wegener's Granulomatosis

Secondary

• Amyloidosis
• Dermatomyositis
• Diabetes Mellitus
• Drugs
• Endocarditis
• Fabry's Disease
• Goodpasture's Syndrome
• Henoch-Schonlein purpura
• HIV
• Infectious Mononeucliosis
• Lipoatrophy
• Lymphomas
• Malaria
• Multiple Myeloma
• Orthostatic Proteinuria
• Polyarteritis Nodosa
• Pre-Eclampsia
• Rheumatoid Arthritis
• Sarcoidosis
• Sickle Cell Anemia
• Sjogren's Syndrome
• Streptococcal Infection
• Syphillis
• Systemic Lupus Erythematosus
• Toxoplasmosis
• Vasculitis
• Viral Hepatitis

Miscellaneous

• Chronic interstitial nephritis
• Graft vs. Host Disease
• Hypothyroidism
• Pre-eclampsia
• Renal vein thrombosis
• Severe Obesity
• Thyroiditis