Iodoquinol

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Iodoquinol
YODOXIN® Package Insert
Description
Inactive Ingredients
Action
Indications
Contraindications
Warnings
Use in Pregnancy
Precautions
Adverse Reactions
Dosage and Administration
How Supplied
Storage

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The quinoline derivative diiodohydroxyquinoline (INN) or iodoquinol (USAN) can be used in the treatment of amebiasis, balantidiasis, and Dientamoeba fragilis.[1] It is poorly absorbed from the gastrointestinal tract and is used as a luminal agent to eradicate both cysts and trophozoites infestating the lumen of the gastrointestinal tract.

Category

Amebicide

US Brand Names

YODOXIN®, ALA-SEPTIC®, ALCORTIN®, ALCORTIN A®, ALOQUIN®, DERMAZENE®, HYDROCORTISONE IODOQUINOL cream®, VYTONE cream®

Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Dosage and Administration | How Supplied | Labels and Packages

Mechanisms of Action

Iodoquinol acts by chelation of Fe2+ which is essential for metabolism.

References

  1. Ghaskadbi S, Vaidya VG (1989). "In vivo antimutagenic effect of ascorbic acid against mutagenicity of the common antiamebic drug diiodohydroxyquinoline". Mutat. Res. 222 (3): 219–22. doi:10.1016/0165-1218(89)90137-7. PMID 2493578. Unknown parameter |month= ignored (help)