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Black Box Warning
Title
See full prescribing information for complete Boxed Warning.
ConditionName:
Content
Overview
Minocycline hydrochloride is a that is FDA approved for the {{{indicationType}}} of . There is a Black Box Warning for this drug as shown here. Common adverse reactions include .
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
Condition1
Dosing Information
Dosage
Condition2
Dosing Information
Dosage
Condition3
Dosing Information
Dosage
Condition4
Dosing Information
Dosage
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
Condition1
Developed by:
Class of Recommendation:
Strength of Evidence:
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Guideline-Supported Use of Minocycline hydrochloride in adult patients.
Non–Guideline-Supported Use
Condition1
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Non–Guideline-Supported Use of Minocycline hydrochloride in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
Condition1
Dosing Information
Dosage
Condition2
There is limited information regarding FDA-Labeled Use of Minocycline hydrochloride in pediatric patients.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
Condition1
Developed by:
Class of Recommendation:
Strength of Evidence:
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Guideline-Supported Use of Minocycline hydrochloride in pediatric patients.
Non–Guideline-Supported Use
Condition1
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Non–Guideline-Supported Use of Minocycline hydrochloride in pediatric patients.
Contraindications
Condition1
Warnings
Title
See full prescribing information for complete Boxed Warning.
ConditionName:
Content
Description
Precautions
Description
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Clinical Trial Experience of Minocycline hydrochloride in the drug label.
Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous
Postmarketing Experience
There is limited information regarding Postmarketing Experience of Minocycline hydrochloride in the drug label.
Australian Drug Evaluation Committee (ADEC) Pregnancy Category
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Minocycline hydrochloride in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Minocycline hydrochloride during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Minocycline hydrochloride with respect to nursing mothers.
Pediatric Use
There is no FDA guidance on the use of Minocycline hydrochloride with respect to pediatric patients.
Geriatic Use
There is no FDA guidance on the use of Minocycline hydrochloride with respect to geriatric patients.
Gender
There is no FDA guidance on the use of Minocycline hydrochloride with respect to specific gender populations.
Race
There is no FDA guidance on the use of Minocycline hydrochloride with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Minocycline hydrochloride in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Minocycline hydrochloride in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Minocycline hydrochloride in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Minocycline hydrochloride in patients who are immunocompromised.
Administration and Monitoring
Administration
Oral
Intravenous
Monitoring
There is limited information regarding Monitoring of Minocycline hydrochloride in the drug label.
Description
IV Compatibility
There is limited information regarding IV Compatibility of Minocycline hydrochloride in the drug label.
Overdosage
Acute Overdose
Signs and Symptoms
Description
Management
Description
Chronic Overdose
There is limited information regarding Chronic Overdose of Minocycline hydrochloride in the drug label.
Pharmacology
There is limited information regarding Minocycline hydrochloride Pharmacology in the drug label.
Mechanism of Action
Structure
MINOCIN® minocycline hydrochloride, is a semisynthetic derivative of tetracycline, 4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride.
MINOCIN® Pellet-Filled Capsules for oral administration contain pellets of minocycline HCl equivalent to 50 mg or 100 mg of minocycline in microcrystalline cellulose.
The capsule shells contain the following inactive ingredients: Blue 1, Gelatin, Titanium Dioxide and Yellow 10. The 50 mg capsule shells also contain Black and Yellow Iron Oxides.
Pharmacodynamics
There is limited information regarding Pharmacodynamics of Minocycline hydrochloride in the drug label.
Pharmacokinetics
There is limited information regarding Pharmacokinetics of Minocycline hydrochloride in the drug label.
Nonclinical Toxicology
There is limited information regarding Nonclinical Toxicology of Minocycline hydrochloride in the drug label.
Clinical Studies
There is limited information regarding Clinical Studies of Minocycline hydrochloride in the drug label.
How Supplied
Storage
There is limited information regarding Minocycline hydrochloride Storage in the drug label.
Images
Drug Images
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