Opioid withdrawal resident survival guide

Jump to navigation Jump to search
Resident Survival Guide
Introduction
Team
Guide
Page Template
Examine the Patient Template
Navigation Bar Template
Checklist
Topics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahmoud Sakr, M.D. [2]

Definition

This section provides a short and straight to the point definition of the disease or symptom in one sentence.

Opioid Peak withdrawal symptoms Duration of symptoms
Heroin 36-72 hours 7-10 days
Methadone 72-96 hours 14 days
Buprenorphine 36-72 hours 7 days

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Management

Shown below is an algorithm summarizing the approach to [[Opioid withdrawal]].

 
 
 
 
 
 
 
Characterize the symptoms:
❑ Flu like illness
❑ Lacrimation/rhinorrhea
❑ Sneezing
❑ Anorexia
❑ Nausea, vomiting & diarrhea
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Examine the patient:
❑ Pupillary dilatation
❑ Gooseflesh (piloerection)
❑ Yawning
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Admit the patient
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Opioid agonists:
❑ Methadone 20-35 mg daily or
❑ Buprenorphine 4-16 mg daily
❑ Taper by 3% daily over next several days
Nonopioid drugs:
❑ Clonidine 0.2 mg every 4 hours tapered after day 3 or
❑ Lofexidine 0.2 mg BD daily, titrated to 1.2 mg BD daily
❑ Treatment duration 10 days for heroin; 14 days for methadone
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

References


Template:WikiDoc Sources