Pancreatitis causes

Pancreatitis Main Page
Patient Information
Overview
Causes
Classification Acute Pancreatitis Chronic Pancreatitis Hereditary Pancreatitis Autoimmune Pancreatitis
Differential Diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Vidit Bhargava, M.B.B.S [2]

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Acute pancreatitis is a life-threatening condition, especially if it progresses to necrotizing pancreatitis, and should be treated as such irrespective of the cause.

Common Causes

• Alcohol 30%

• Gallstones 35-40%

• Hypertriglyceridemia 1-4% cases

• Medication such as 5-mercaptopurine, azathioprine, 5-DDI

• Pancreatic tumor

• Post-ERCP

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	Atheroembolism , Cholesterol embolism, Hemorrhagic shock , Hypotension, Intraoperative hypotension
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	6-mercaptopurine, Acetaminophen, Amiodarone, Arabinoside, Asparaginase, Azathioprine, Azodisalicylate, Bexarotene, Bezafibrate, Bumetanide, Carbimazole, Chlorothiazide, Clomiphene, Clozapine, Cytosine, Dapsone, Dexamethasone, Didanosine, Enalapril, Enfuvirtide, Erythromycin, Estrogen, Exenatide, Frusemide, Furosemide, Ifosfamide, Isoniazid, Lamivudine, Linagliptin, Liraglutide, Losartan, Meglumine, Mesalamine, Mesalazine, Methimazole, Methyldopa, Metronidazole, Nelfinavir, Nitrofurantoin, Olsalazine, Omeprazole, Oxyphenbutazone, Pegaspargase, Pentamidine, Phenylbutazone, Ponatinib, Pravastatin, Premarin, Procainamide, Propofol, Pyritonol, Simvastatin, Sitagliptin, Stavudine, Stibogluconate, Sulfamethoxazole, Sulindac, Tamoxifen, Teduglutide, Tetracycline, Trimethoprimsulfamethazole, Valproic acid, Zalcitabine, Α-methyldopa
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	Alcoholism, Blunt trauma, Pregnancy
Gastroenterologic	Acute gestational fatty liver, Acute hepatic porphyrias, Acute intermittent porphyria, Biliary sludge, Choledochal cyst, Choledocholithiasis, Cholelithiasis, Duodenal ulcer, Gallstones, Gastric ulcer, Hepatitis b , Hereditary pancreatitis, Microlithiasis, Pancreatic cysts, Pancreatic pseudocyst, Porphyrias, Reye syndrome
Genetic	Aminoaciduria, Apolipoprotein c-ii deficiency, Congenital generalized lipodystrophy type 1, Congenital generalized lipodystrophy type 2, Cystic fibrosis, Erythropoietic protoporphyria., Familial hypertriglyceridaemia, Hemochromatosis, Hereditary coproporphyria, Lipoprotein lipase deficiency
Hematologic	No underlying causes
Iatrogenic	ERCP, Partial pancreas resection, Posttransplantation
Infectious Disease	Ascariasis, Aspergillus, Campylobacter jejuni, Coxsackievirus, Cryptosporidium, Cytomegalovirus, Fungal infections, Herpes simplex, HIV, Human enterovirus b, Legionella, Leptrospira, Leukocytosis, Mumps, Mycoplasma, Salmonella, Teniasis, Toxoplasma, Varicella zoster
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	All-trans-retinoic acid, Hypercalcaemia, Hypertriglyceridemia, Zinc
Obstetric/Gynecologic	No underlying causes
Oncologic	Cholangiocarcinoma, Pancreatic cancer
Ophthalmologic	No underlying causes
Overdose/Toxicity	Cannabis, Codeine, Ethanol, Thallium
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Autoimmune pancreatitis, Autoimmune sclerosing pancreatitis, Crohn's disease, Necrotizing vascular angiitis, Polyarteritis nodosa, Systemic lupus erythematosus, Thrombotic thrombocytopenic purpura, Variegate porphyria, Vasculitis
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	Duodenal diverticulum, Ectopic pancreas, Fever, Hypothermia, Idiopathic, Pancreas divisum, Penetrating trauma, Stenosis of pancreatic ducts, Trauma

Causes in Alphabetical Order

• 6-mercaptopurine

• Acetaminophen

• Acute gestational fatty liver

• Acute hepatic porphyrias

• Acute intermittent porphyria

• Alcoholism

• All-trans-retinoic acid

• Aminoaciduria

• Amiodarone

• Apolipoprotein c-ii deficiency

• Arabinoside

• Ascariasis

• Asparaginase

• Aspergillus

• Atheroembolism

• Autoimmune pancreatitis

• Autoimmune sclerosing pancreatitis

• Azathioprine

• Azodisalicylate

• Bexarotene

• Bezafibrate

• Biliary sludge

• Blunt trauma

• Bumetanide

• Campylobacter jejuni

• Cannabis

• Carbimazole

• Chlorothiazide

• Cholangiocarcinoma

• Choledochal cyst

• Choledocholithiasis

• Cholelithiasis

• Cholesterol embolism

• Clomiphene

• Clozapine

• Codeine

• Congenital generalized lipodystrophy type 1

• Congenital generalized lipodystrophy type 2

• Coxsackievirus

• Crohn's disease

• Cryptosporidium

• Cystic fibrosis

• Cytomegalovirus

• Cytosine

• Dapsone

• Dexamethasone

• Didanosine

• Duodenal diverticulum

• Duodenal ulcer

• Ectopic pancreas

• Enalapril

• Enfuvirtide

• Ercp

• Erythromycin

• Erythropoietic protoporphyria.

• Estrogen

• Ethanol

• Exenatide

• Familial hypertriglyceridaemia

• Fever

• Frusemide

• Fungal infections

• Furosemide

• Gallstones

• Gastric ulcer

• Hemochromatosis

• Hemorrhagic shock

• Hepatitis b

• Hereditary coproporphyria

• Hereditary pancreatitis

• Herpes simplex

• Hiv

• Human enterovirus b

• Hypercalcaemia

• Hypertriglyceridemia

• Hypotension

• Hypothermia

• Idiopathic

• Ifosfamide

• Intraoperative hypotension

• Isoniazid

• Lamivudine

• Legionella

• Leptrospira

• Leukocytosis

• Linagliptin

• Lipoprotein lipase deficiency

• Liraglutide

• Losartan

• Meglumine

• Mesalamine

• Mesalazine

• Methimazole

• Methyldopa

• Metronidazole

• Microlithiasis

• Mumps

• Mycoplasma

• Necrotizing vascular angiitis
• Nelfinavir
• Nitrofurantoin
• Mestranol
• Olsalazine
• Omeprazole
• Oxyphenbutazone
• Pancreas divisum
• Pancreatic cancer
• Pancreatic cysts
• Pancreatic pseudocyst
• Partial pancreas resection
• Pegaspargase
• Penetrating trauma
• Pentamidine
• Phenylbutazone
• Polyarteritis nodosa
• Ponatinib
• Porphyrias
• Post transplantation
• Pravastatin
• Pregnancy
• Premarin
• Procainamide
• Propofol
• Pyritonol
• Renal failure
• Reye syndrome
• Salmonella
• Simvastatin
• Sitagliptin
• Smoking
• Stavudine
• Stenosis of pancreatic ducts
• Sodium stibogluconate
• Sulfamethoxazole
• Sulindac
• Systemic lupus erythematosus
• Tamoxifen
• Teduglutide
• Teniasis
• Tetracycline
• Thallium
• Thrombotic thrombocytopenic purpura
• Toxoplasma
• Trauma
• Trimethoprim-sulfamethazole
• Valproic acid
• Varicella zoster
• Variegate porphyria
• Vasculitis
• Zalcitabine
• Zinc
• α-methyldopa