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Acute Pyelonephritis, Outpatient
Preferred Regimen
▸
Ciprofloxacin
500 mg PO q12h for 7 days
WITH OR WITHOUT
▸
Ciprofloxacin
400 mg IV x 1 dose
Alternative Regimen
▸
Ciprofloxacin
1000 mg PO q24h for 7 days
OR
▸
Levofloxacin
750 mg PO q24h for 5 days
OR
▸
TMP/SMZ
160/800 mg PO q12h for 14 days
If FQ resistance >10%, add 1 IV dose of
Ceftriaxone
1 g
OR
Gentamicin
5–7 mg/kg
.
Acute Pyelonephritis, Inpatient
Preferred Regimen
▸
Ciprofloxacin
400 mg IV q12h
OR
▸
Levofloxacin
750 mg IV q24h
OR
▸
Gentamicin
3–5 mg/kg/day IV
OR
▸
Cefriaxone
1–2 gm IV q24h
OR
▸
Cefotaxime
2 gm IV q8h'
OR
▸
Piperacillin/Tazobactam
3.375 gm IV q4–6h
OR
▸
Ertapenem
1 gm IV q24h
OR
▸
Doripenem
500 mg IV q8h
The choice of antiobiotics should be based on resistance pattern.
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