Lopressor injection/adult indications and dosage
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FDA-Labeled Indications and Dosage (Adult)
Myocardial Infarction
- Upon patient presentation: Lopressor injection 5 mg IV x 3 boluses at 2-min intervals
- Fifteen minutes later full IV dose: Lopressor tablet 50 mg PO q6h for 2 days
- If unable to tolerate the full IV dose: Lopressor tablet 25—50 mg PO q6h for 2 days
Lopressor injection is indicated in the treatment of hemodynamically stable patients with definite or suspected acute myocardial infarction to reduce cardiovascular mortality when used in conjunction with oral Lopressor maintenance therapy. Treatment with Lopressor injection can be initiated as soon as the patient’s clinical condition allows.[1]
Off-Label Use and Dosage (Adult)
Cardiac Dysrhythmia
Lopressor injection (range: 2—15 mg) has been shown to be effective in the treatment of atrial flutter, atrial fibrillation, multifocal atrial tachycardia, and supraventricular tachycardia.[2]
Injection Site Pain Associated with Propofol
Pretreatment with Lopressor injection (2 mg IV) was shown to be equally as effective as lidocaine in reducing the pain associated with propofol injection.[3]
References
- ↑ "LOPRESSOR (METOPROLOL TARTRATE) INJECTION, SOLUTION [NOVARTIS PHARMACEUTICALS CORPORATION]".
- ↑ Amsterdam, EA.; Kulcyski, J.; Ridgeway, MG. (1991). "Efficacy of cardioselective beta-adrenergic blockade with intravenously administered metoprolol in the treatment of supraventricular tachyarrhythmias". J Clin Pharmacol. 31 (8): 714–8. PMID 1880230. Unknown parameter
|month=ignored (help) - ↑ Aşik, I.; Yörükoğlu, D.; Gülay, I.; Tulunay, M. (2003). "Pain on injection of propofol: comparison of metoprolol with lidocaine". Eur J Anaesthesiol. 20 (6): 487–9. PMID 12803269. Unknown parameter
|month=ignored (help)