Metoprolol
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms / Brand Names: Lopressor, Toprol XL, Toprolxl XL
Overview
Metoprolol is a competitive, β1-selective (cardioselective) blocker used in treatment of angina pectoris, hypertension, arrhythmia, and migraine. Common adverse reactions include bradyarrhythmia, heart block, heart failure, hypotension, pruritus, rash, constipation, diarrhea, indigestion, nausea, dizziness, fatigue, headache, depression, dyspnea, and wheezing.
The active substance metoprolol is employed either as metoprolol succinate or as metoprolol tartrate (where 100 mg metoprolol tartrate corresponds to 95 mg metoprolol succinate). The tartrate is an immediate-release and the succinate is an extended-release formulation.[1]
Category
Anti-anginal, antiarrhythmic, beta-adrenergic blocker
Prescribing Information
Metoprolol Succinate
Metoprolol Succinate/Hydrochlorothiazide
Metoprolol Tartrate
Metoprolol Tartrate/Arginine
Metoprolol Tartrate/Hydrochlorothiazide
References
- ↑ Cupp M (2009). "Alternatives for Metoprolol Succinate" (pdf). Pharmacist's Letter / Prescriber's Letter. 25 (250302).