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FIRE: Focused Initial Rapid Evaluation

A Focused Initial Rapid Evaluation (FIRE) should be performed to identify patients in need of immediate intervention.

Boxes in the salmon color signify that an urgent management is needed.

Abbreviations: CBC, complete blood count; CI, cardiac index; CK-MB, creatine kinase MB isoform; CVP, central venous pressure; DC, differential count; ICU, intensive care unit; INR, international normalized ratio; LFT, liver function test; MAP, mean arterial pressure; MVO2, mixed venous oxygen saturation; PCWP, pulmonary capillary wedge pressure; PT, prothrombin time; PTT, partial prothrombin time; SaO2, arterial oxygen saturation; SBP, systolic blood pressure; SCVO2, central venous oxygen saturation; SMA-7, sequential multiple analysis-7.

 
 
 
 
Does the patient have cardinal findings that increase the pretest probability of cardiogenic shock?

❑  Evidence of hypoperfusion

❑  Altered mental status
❑  Cool extremities
❑  Cyanosis
❑  Oliguria
❑  Sustained hypotension
❑  SBP <90 mm Hg for ≥30 min or
❑  MAP ↓ >30 mm Hg below baseline for ≥30 min
❑  Presence of myocardial dysfunction after exclusion or correction of non-myocardial factors contributing to tissue hypoperfusion
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
YES
 
 
 
 
 
NO
 
 
 
 
 
 
 
 
 
 
 
 
 
Cardiogenic
shock
suspected
 
 
 
 
 
Proceed to
shock resident survival guide
to identify and correct the cause
 
 
 
 
 
 
 
 
 
 
 
 
Immediate management

❑  Intubation with mechanical ventilation

❑  ± IV bolus normal saline 100–200 mL

❑  ± Norepinephrine 0.1–2.0 μg/kg/min

❑  ± Control pain and/or anxiety

❑  Morphine sulphate
❑  Fentanyl
❑  Cardiology consultation
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Immediate goals

❑  SaO2 >90%–92%

❑  CVP 8–12 mm Hg

❑  MAP >60 mm Hg

❑  PCWP 14–18 mm Hg

❑  CI >2.2 L/min/m2

❑  MVO2 >60%

❑  SCVO2 >70%

❑  Hemoglobin >7–9 g/dL

❑  Lactate <2.2 mM/L

❑  Urine output >0.5 mL/kg/h

❑  ± Correct arrhythmia

❑  ± Correct electrolyte disturbance