Sandbox/osteo

Hematogenous Osteomyelitis

Empiric Therapy

▸ Click on the following categories to expand treatment regimens.

Age   ▸  Newborn (<4 months)   ▸  Children (>4 months) - Adults   ▸  Adult (>21 years)

Staph aureus, gram-negative bacilli, group B strept Preferred Regimen ▸ Vancomycin 40 mg divided q6-8 hours PLUS ▸ Ceftazidime 50 mg IV q8h OR ▸ Cefepime 150 mg IV q8h Alternative Regimen ▸ Nafcillin OR ▸ Oxcacillin 37mg q6h PLUS ▸ Ceftazidime 2 gm IV q8h OR Cefepime 2 gm IV q12h Staph aureus, group A strept, gram-negative bacilli Preferred Regimen ▸ Vancomycin 40 mg divided q6-8 hours PLUS ▸ Ceftazidime 50 mg IV q8h OR ▸ Cefepime 150 mg IV q8h Alternative Regimen ▸ Nafcillin OR ▸ Oxcacillin 37mg q6h PLUS ▸ Ceftazidime 2 gm IV q8h OR Cefepime 2 gm IV q12h Staph aureus (most common) Preferred Regimen ▸ Vancomycin 1 gm IV q12h, if over 100 kg, 1.5 gm IV q12h Alternative Regimen ▸ Nafcillin 2 gm IV q4h OR ▸ Oxacillin 2 gm IV q4h