Lithium carbonate
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
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Overview
Lithium carbonate is a mood Stabilizer that is FDA approved for the {{{indicationType}}} of bipolar disorder, maintenance therapy and manic episode. Common adverse reactions include acne, hypothyroidism, weight increased, gastritis, nausea, xerostomia, leukocytosis, fine tremor, hyperreflexia, deep tendon, nephrotoxicity, polyuria, increased thirst.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
- Bipolar disorder, maintenance therapy
- Maintenance 900 to 1200 mg/day PO in 2 to 3 divided doses
- Bipolar disorder, manic episode
- 1800 mg/day PO in 2 to 3 divided doses
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Lithium carbonate in adult patients.
Non–Guideline-Supported Use
There is limited information about Off-Label Non–Guideline-Supported Use of Lithium carbonate in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
- Safety below the age of 12 have not been established.
- Bipolar disorder, maintenance therapy
- 12 yr and older, extended-release tablets, maintenance, 900 to 1200 mg/day PO in 2 to 3 divided doses; desired serum lithium levels ranging between 0.6 to 1.2 mEq/L
- Bipolar disorder, maintenance therapy
- Immediate-release tablet and capsule formulations, maintenance, 300 mg PO 3 to 4 times daily
Bipolar disorder, manic episode
- 12 yr and older, extended-release tablets, acute mania, 1800 mg/day PO in 2 to 3 divided doses
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Lithium carbonate in pediatric patients.
Non–Guideline-Supported Use
There is limited information about Off-Label Non–Guideline-Supported Use of Lithium carbonate in pediatric patients.
Contraindications
There is limited information regarding Lithium carbonate Contraindications in the drug label.
Warnings
There is limited information regarding Lithium carbonate Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Lithium carbonate Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Lithium carbonate Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Lithium carbonate Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Lithium carbonate in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Lithium carbonate in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Lithium carbonate during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Lithium carbonate in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Lithium carbonate in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Lithium carbonate in geriatric settings.
Gender
There is no FDA guidance on the use of Lithium carbonate with respect to specific gender populations.
Race
There is no FDA guidance on the use of Lithium carbonate with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Lithium carbonate in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Lithium carbonate in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Lithium carbonate in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Lithium carbonate in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Lithium carbonate Administration in the drug label.
Monitoring
There is limited information regarding Lithium carbonate Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Lithium carbonate and IV administrations.
Overdosage
There is limited information regarding Lithium carbonate overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
There is limited information regarding Lithium carbonate Pharmacology in the drug label.
Mechanism of Action
There is limited information regarding Lithium carbonate Mechanism of Action in the drug label.
Structure
There is limited information regarding Lithium carbonate Structure in the drug label.
Pharmacodynamics
There is limited information regarding Lithium carbonate Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Lithium carbonate Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Lithium carbonate Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Lithium carbonate Clinical Studies in the drug label.
How Supplied
There is limited information regarding Lithium carbonate How Supplied in the drug label.
Storage
There is limited information regarding Lithium carbonate Storage in the drug label.
Images
Drug Images
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Package and Label Display Panel
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Patient Counseling Information
There is limited information regarding Lithium carbonate Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Lithium carbonate interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
There is limited information regarding Lithium carbonate Brand Names in the drug label.
Look-Alike Drug Names
There is limited information regarding Lithium carbonate Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.