Isocarboxazid
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
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Black Box Warning
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Warning Title
See full prescribing information for complete Boxed Warning.
Condition Name: (Content)
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Overview
Isocarboxazid is a MAOI that is FDA approved for the {{{indicationType}}} of depression. There is a Black Box Warning for this drug as shown here. Common adverse reactions include constipation, nausea, xerostomia, dizziness, headache, insomnia..
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
- Depression
- Initial: 20 mg/day PO into 2 doses, increase every 2-4 days by 10 mg, to a maximum of 40 mg in first week. Then increase to 20 mg/week to a max of 60 mg/day.
- Maintenance: Decrease dose slowly to minimum effective dosage
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Isocarboxazid in adult patients.
Non–Guideline-Supported Use
There is limited information about Off-Label Non–Guideline-Supported Use of Isocarboxazid in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
safety in under 16 years of age have not been established.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information about Off-Label Guideline-Supported Use of Isocarboxazid in pediatric patients.
Non–Guideline-Supported Use
There is limited information about Off-Label Non–Guideline-Supported Use of Isocarboxazid in pediatric patients.
Contraindications
There is limited information regarding Isocarboxazid Contraindications in the drug label.
Warnings
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Warning Title
See full prescribing information for complete Boxed Warning.
Condition Name: (Content)
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There is limited information regarding Isocarboxazid Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Isocarboxazid Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Isocarboxazid Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Isocarboxazid Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Isocarboxazid in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Isocarboxazid in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Isocarboxazid during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Isocarboxazid in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Isocarboxazid in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Isocarboxazid in geriatric settings.
Gender
There is no FDA guidance on the use of Isocarboxazid with respect to specific gender populations.
Race
There is no FDA guidance on the use of Isocarboxazid with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Isocarboxazid in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Isocarboxazid in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Isocarboxazid in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Isocarboxazid in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Isocarboxazid Administration in the drug label.
Monitoring
There is limited information regarding Isocarboxazid Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Isocarboxazid and IV administrations.
Overdosage
There is limited information regarding Isocarboxazid overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
Mechanism of Action
There is limited information regarding Isocarboxazid Mechanism of Action in the drug label.
Structure
There is limited information regarding Isocarboxazid Structure in the drug label.
Pharmacodynamics
There is limited information regarding Isocarboxazid Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Isocarboxazid Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Isocarboxazid Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Isocarboxazid Clinical Studies in the drug label.
How Supplied
There is limited information regarding Isocarboxazid How Supplied in the drug label.
Storage
There is limited information regarding Isocarboxazid Storage in the drug label.
Images
Drug Images
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Package and Label Display Panel
{{#ask: Label Page::Isocarboxazid |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}
Patient Counseling Information
(Patient Counseling Information)
Precautions with Alcohol
Alcohol-Isocarboxazid interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
There is limited information regarding Isocarboxazid Brand Names in the drug label.
Look-Alike Drug Names
There is limited information regarding Isocarboxazid Look-Alike Drug Names in the drug label.
Drug Shortage Status
Drug Shortage
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
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