Chronic myelogenous leukemia epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]

Overview

Chronic myelogenous leukemia (CML) occurs in all age groups, but most commonly in the middle-aged and elderly. CML affects slightly more men than women. CML represents about 15–20% of all cases of adult leukemia in Western populations.^[1] In 2011, the age-adjusted incidence of CML was 1.81 per 100,000 persons in the United States.^[2]

Epidemiology

Incidence

In 2011, the age-adjusted incidence of CML was 1.81 per 100,000 persons in the United States.^[2]

Age

While the overall age-adjusted incidence of CML in the United States between 2007 and 2011 is 1.7 per 100,000, the age-adjusted incidence of CML by age category is:^[2]
- Under 65 years: 0.9 per 100,000
- 65 and over: 6.8 per 100,000

Gender

In the United States, the age-adjusted incidence of CML by gender on 2011 is:^[2]
- In males: 2.42 per 100,000 persons
- In females: 1.30 per 100,000 persons

Shown below is an image depicting the observed incidence of myeloid leukemia by gender in the United States between 1975 and 2011. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.^[2]

References

↑ Faderl S, Talpaz M, Estrov Z, Kantarjian HM (1999). "Chronic myelogenous leukemia: biology and therapy". Annals of Internal Medicine. 131 (3): 207–219. PMID 10428738.
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.

Template:WikiDoc Sources

[Faderl1990-1] Faderl S, Talpaz M, Estrov Z, Kantarjian HM (1999). "Chronic myelogenous leukemia: biology and therapy". Annals of Internal Medicine. 131 (3): 207–219. PMID 10428738.

[SEER-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.

[1]

[2]