Dengue fever natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Dengue fever generally lasts a week or more, and can rarely be complicated by bleeding, febrile convulsions and coma. While the disease is generally non-fatal, Dengue fever can be life-threatening in people with chronic diseases such as diabetes and asthma.
Natural History
- Dengue fever generally lasts about six to seven days, with a smaller peak of fever at the trailing end of the fever (the so-called "biphasic pattern"). The platelet count will drop until the patient's temperature is normal.[1]
Complications
Possible complications of Dengue fever include:[2]
- Acute respiratory failure[3]
- Bleeding, specially upper gastrointestinal bleeding
- Febrile convulsions
- Neurological:[4] Central nervous system hemorrhage, coma, encephalitis, encephalomyelitis, Guillain-Barre syndrome, myelitis, neuropathy,
- Severe dehydration
- Shock
Prognosis
Although uncomfortable, dengue fever is generally not deadly.[1]. Mortality rates between 0% and 5.4% have been reported.[5]16899384 Dengue fever can be life-threatening in people with chronic diseases such as diabetes and asthma.
References
- ↑ 1.0 1.1 "Dengue: guidelines for diagnosis, treatment, prevention and control" (PDF).
- ↑ Halstead SB (2007). "Dengue". Lancet. 370 (9599): 1644–52. doi:10.1016/S0140-6736(07)61687-0. PMID 17993365.
- ↑ Wang CC, Liu SF, Liao SC, Lee IK, Liu JW, Lin AS; et al. (2007). "Acute respiratory failure in adult patients with dengue virus infection". Am J Trop Med Hyg. 77 (1): 151–8. PMID 17620647.
- ↑ Puccioni-Sohler M, Orsini M, Soares CN (2012). "Dengue: a new challenge for neurology". Neurol Int. 4 (3): e15. doi:10.4081/ni.2012.e15. PMC 3555217. PMID 23355928.
- ↑ Guzmán MG, Kourí G (2002). "Dengue: an update". Lancet Infect Dis. 2 (1): 33–42. PMID 11892494.