WBR0657
| Author | [[PageAuthor::Anonymous (Reviewed by Alison Leibowitz)]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Pathophysiology |
| Sub Category | SubCategory::Gastrointestinal |
| Prompt | [[Prompt::An obese, multiparous, 48-year-old female presents to the physician's office with a nonradiating right upper quadrant abdominal pain with bloating, nausea, and vomiting that worsens after the consumption of fries and a hamburger. Abdominal ultrasonography displays hyperechogenic foci within the thickened gallbladder wall. Laboratory testing reveals a WBC count of 16,000/μL and serum amylase and lipase levels of 75 U/L and 150 U/L, respectively. Which of the following secreted substances most likely accounts for her abdominal pain?]] |
| Answer A | AnswerA::Cholecystokinin |
| Answer A Explanation | AnswerAExp::See overall explanation |
| Answer B | AnswerB::Gastrin |
| Answer B Explanation | AnswerBExp::See overall explanation |
| Answer C | AnswerC::Pepsin |
| Answer C Explanation | AnswerCExp::See overall explanation |
| Answer D | AnswerD::Secretin |
| Answer D Explanation | AnswerDExp::See overall explanation |
| Answer E | AnswerE::Gastric inhibitory peptide |
| Answer E Explanation | AnswerEExp::See overall explanation |
| Right Answer | RightAnswer::A |
| Explanation | [[Explanation::The patient in this scenario demonstrates classic findings of acute calculous cholecystitis. Acute calculous cholecystitis typically develops in patients who fit the profile of the 4F's: Female, Fat, Fertile, and in her Forties. Strenuous contraction of the gallbladder, described as a nonradiating abdominal pain in the right upper quadrant, is secondary to the effect of cholecystokinin, which is secreted in response to ingestion of lipids and proteins.
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| Approved | Approved::No |
| Keyword | WBRKeyword::Cholelithiasis, WBRKeyword::Cholecystitis, WBRKeyword::Cholecystokinin |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |
