Retroperitoneal fibrosis medical therapy

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Retroperitoneal fibrosis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Medical Therapy

In the absence of severe urinary tract obstruction (which generally requires surgery with omental wrapping) treatment is generally with glucocorticoids initially, followed by DMARDs either as steroid-sparing agents or if refractory on steroids. The SERM tamoxifen has shown to improve the condition in various small trials, although the exact mechanism of its action remains unclear.

References

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