Enterovirus 68 overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]; João André Alves Silva, M.D. [3]
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Enterovirus 68 overview On the Web | |
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American Roentgen Ray Society Images of Enterovirus 68 overview | |
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Risk calculators and risk factors for Enterovirus 68 overview | |
Overview
Enterovirus 68 (EV68) is a member of the Enterovirus genus of the Picornaviridae family. It is a non-enveloped, positive-sense, single-stranded RNA virus. It is detected more frequently among pediatric patients in the United States and other countries. While enteroviruses can cause a wide range of symptoms ranging from mild febrile illness to fatal meningitis and encephalitis, EV68 is mostly associated with acute respiratory symptoms. In 2014, EV68 was isolated from 2 children with a polio-like flaccid paralysis; however, the virus could not be isolated among 3 other kids with a similar presentation.
Historical Perspective
Pathophysiology
Causes
Differentiating Enterovirus 68 from other Diseases
Enterovirus 68 infection must be differentiated from other diseases that cause fever, cough, malaise, and rhinorrhea such as: respiratory syncytial virus, adenovirus, parainfluenza virus, seasonal influenza virus B, coronavirus, and rhinovirus.
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
History and Symptoms
Enterovirus 68 infection presents with symptoms of an acute respiratory tract infection. The most common symptoms of this viral infection include fever, cough, dyspnea, rhinorrhea, and malaise.