Cutaneous small vessel vasculitis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2].

Synonyms and keywords: Cutaneous leukocytoclastic angiitis, cutaneous leukocytoclastic vasculitis, cutaneous necrotizing venulitis, hypersensitivity angiitis.

Overview

Cutaneous small-vessel vasculitis (also known as "Cutaneous leukocytoclastic angiitis,"^[1] "Cutaneous leukocytoclastic vasculitis,"^[1] "Cutaneous necrotizing venulitis,"^[1] and "Hypersensitivity angiitis"^[1]) is inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura.^[2]^:831^[3] It is the most common vasculitis seen in clinical practice. Leukocytoclasis refers to the damage caused by nuclear debris from infiltrating neutrophils in and around the vessels.^[4]

Subtypes of small-vessel vasculitis include:^[2]^:833–6

Physical examination

Gallery

Skin

Extremities

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Trunk

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References

↑ ^1.0 ^1.1 ^1.2 ^1.3 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
↑ ^2.0 ^2.1 James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
↑ Lotti T, Ghersetich I, Comacchi C, Jorizzo JL (November 1998). "Cutaneous small-vessel vasculitis". J. Am. Acad. Dermatol. 39 (5 Pt 1): 667–87, quiz 688–90. doi:10.1016/S0190-9622(98)70039-8. PMID 9810883.
↑ Harrison's Principles of Internal Medicine. 18th edition. Page 2798.

[Bolognia-1] 1.0 ^1.1 ^1.2 ^1.3 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.

[Andrews-2] 2.0 ^2.1 James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.

[pmid9810883-3] Lotti T, Ghersetich I, Comacchi C, Jorizzo JL (November 1998). "Cutaneous small-vessel vasculitis". J. Am. Acad. Dermatol. 39 (5 Pt 1): 667–87, quiz 688–90. doi:10.1016/S0190-9622(98)70039-8. PMID 9810883.

[4] Harrison's Principles of Internal Medicine. 18th edition. Page 2798.

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