Sandbox/HIV

Recommended Treatment of Chronic Hepatitis B

Coinfection	Natural history	Treatment	Prevention
+	≤2 x Upper Limit of Normal	>20,000 IU/mL	Low efficacy with present treatment Observe: treatment should be considered as ALT rises Biopsy should be considered in adults >40years, when: Persistence of an elevated ALT: [Normal;<2xUpper Limit of Normal] Family history of hepatocellular carcinoma Treatment should be considered when: HBV DNA > 20,000 IU/mL Signs of inflammation (moderate to severe) or fibrosis on biopsy