Naproxen sodium
Synonyms / Brand Names: Aleve, Anaprox, Bonyl, DL Naproxen, DL-Naproxen, Diocodal, Dysmenalgit, Ec-naprosyn, Equiproxen, Floginax, Laraflex, Laser, Mnpa, Naixan, Naprelan, Napren, Naprium, Naprius, Naprosine, Naprosyn, Naprosyne, Naproxen Sodium, Naprux, Naxen, Naxyn, Niaxan, Nycopren, Panoxen, Pranoxen, Prexan, Proxen, Proxine, Reuxen, Veradol, Xenar x
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Dosing and Administration
Geriatric Patients
Studies indicate that although total plasma concentration of Naproxen is unchanged, the unbound plasma fraction of Naproxen is increased in the elderly. Caution is advised when high doses are required and some adjustment of dosage may be required in elderly patients. As with other drugs used in the elderly, it is prudent to use the lowest effective dose.
Patients with Moderate to Severe Renal Impairment
Naproxen-containing products are not recommended for use in patients with moderate to severe and severe renal impairment (creatinine clearance < 30 mL/min).
Rheumatoid Arthritis, Osteoarthritis and Ankylosing Spondylitis
- 275 mg (Naproxen 250 mg with 25 mg sodium) twice daily
- or 550 mg (Naproxen 500 mg with 50 mg sodium) twice daily
For more information on dosing please refer to Instructions for administration
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Naproxen sodium
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Publication Resources
Most Recent Articles on Naproxen sodium
Review Articles on Naproxen sodium
Articles on Naproxen sodium in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Naproxen sodium
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Trial Resources
Ongoing Trials with Naproxen sodium at Clinical Trials.gov
Trial Results with Naproxen sodium
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Naproxen sodium
Cochrane Collaboration on Naproxen sodium
Cost Effectiveness of Naproxen sodium
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Media Resources
Powerpoint Slides on Naproxen sodium
Images of Naproxen sodium
Podcasts & MP3s on Naproxen sodium
Videos on Naproxen sodium
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Patient Resources
Patient Resources on Naproxen sodium
Discussion Groups on Naproxen sodium
Patient Handouts on Naproxen sodium
Blogs on Naproxen sodium
Naproxen sodium in the News
Naproxen sodium in the Marketplace
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International Resources
Naproxen sodium en Español
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Adapted from the FDA Package Insert.