Opioid intoxication

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Differential Diagnosis

  • Other substance intoxication
  • Other opioid-related disorders

Diagnostic Criteria

DSM-V Diagnostic Criteria for Opioid Intoxication[1]

  • A.Recent use of an opioid.

AND

  • B.Clinically significant problematic behavioral or psychological changes (e.g., initial euphoria followed by apathy, dysphoria, psychomotor agitation or retardation, impaired judgment) that developed during, or shortly after, opioid use.

AND

  • C.Pupillary constriction (or pupillary dilation due to anoxia from severe overdose) and one (or more) of the following signs or symptoms developing during, or shortly after,

opioid use:

  • 1.Drowsiness or coma.
  • 2.Slurred speech.
  • 3.Impairment in attention or memory.

AND

  • D.The signs or symptoms are not attributable to another medical condition and are not better explained by another mental disorder, including intoxication with another substance.

Specify if:

  • With perceptual disturbances: This specifier may be noted in the rare instance in which hallucinations with intact reality testing or auditory, visual, or tactile illusions occur in the absence of a delirium.

References

  1. 1.0 1.1 Diagnostic and statistical manual of mental disorders : DSM-5. Washington, D.C: American Psychiatric Association. 2013. ISBN 0890425558.