Dicycloverine

Dicycloverine

File:Dicyclomine-trans.png
Clinical data
ATC code	A03AA07 (WHO)
Pharmacokinetic data
Protein binding	>99%
Identifiers
IUPAC name 2-diethylaminoethyl1- cyclohexylcyclohexane- 1-carboxylate
CAS Number	77-19-0
PubChem CID	3042
DrugBank	APRD00113
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C19H35NO2
Molar mass	309.487 g/mol

Dicyclomine is an anticholinergic that blocks muscarinic receptors. Dicyclomine is known as dicycloverine hydrochloride in the UK.

Clinical uses

Dicyclomine is used to treat intestinal hypermotility, the symptoms of Irritable Bowel Syndrome (IBS) (also known as spastic colon). It relieves muscle spasms in the gastrointestinal tract by blocking the activity of a certain natural substance in the body. It is a smooth muscle relaxer.

In America, it is sold under the trade names: Bentyl, Byclomine, Dibent, Di-Spaz, Dilomine.

It is sold under the trade names Bentylol (Hoechst Marion Roussel), Formulex (ICN), and Lomine (Riva) in Canada.

Sources

• Brenner, G. M. (2000). Pharmacology. Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
• Canadian Pharmacists Association (2000). Compendium of Pharmaceuticals and Specialties (25th ed.). Toronto, ON: Webcom. ISBN 0-919115-76-4

External links

• Dicyclomine on Medicine Net
• Dicyclomine on Medline Plus