Flurbiprofen (oral)
File:Flurbiprofen.svg | |
Clinical data | |
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Pregnancy category | |
Routes of administration | Oral |
ATC code | |
Pharmacokinetic data | |
Protein binding | > 99% |
Metabolism | Hepatic (CYP2C9) |
Elimination half-life | 4.7-5.7 hours |
Excretion | Renal |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C15H13FO2 |
Molar mass | 244.261 g/mol |
Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. It is also known by the trade name ANSAID and marketed by Pfizer.
Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges.
R-flurbiprofen is the single enantiomer of racemate flurbiprofen; this compound is currently in clinical trials for the treatment of metastatic prostate cancer, and Alzheimer's disease.
Flurbiprofen was mocked by television satirist Stephen Colbert (for its unlikely name) during an interview with Terry Gross aired on October 9, 2007 on National Public Radio's program "Fresh Air." Colbert had been taking the drug after breaking his wrist earlier that year.
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